Effect of Surface Treatment Method of Light-Cured Material on Its Toxic Properties

In recent decades, a large number of different nanocomposite materials have appeared, which have found wide application in almost all areas of life, including medicine. However, to date, the properties of these materials have not been completely studied. The evaluation of toxicity and biocompatibility is particularly relevant. In this regard, this study aimed to investigate the effect of the surface treatment method of light-cured material on its toxic properties for normal fibroblasts. For this purpose, light-cured nanohybrid composite material Herculite XRV Ultra in the form of 10×5 mm plates (smooth and notched) were incubated with a culture of rat fibroblasts, after that, morphological changes were assessed, and "toxic exposure zones" (a distance from the test plate to a layer of intact fibroblasts) were measured. As a result, it was ascertained that although the investigated material has moderate toxicity to normal cells of the organism, the degree of the nanocomposite toxicity and, in particular, the size of the zone of toxic influence is significantly affected by the properties of its surface, depending on the mechanical action on the restorative material.