Clinic-morphological diagnosis of Barrett’s esophagus

Objective. Determination of efficacy of morphological diagnosis of the Barrett’s esophagus (BE). Маterials and methods. Diagnosis of BE in accordance to data obtained during screening endoscopic investigation with biopsy and morphological verification in 2014 - 2016 yrs, basing on Medical Centre «University Clinic «Оberig», Kyiv, was analyzed. Results. BE was diagnosed in 841 (36.8%) patients (95% of confidence interval (CІ) 36.02 – 39.76) among 2405 patients, in whom esophagogastroscopy was conducted. Histologically cardiac metaplasia was revealed in 48 (5.71%) patients, fundic - in 136 (16.19%), intestinal specialized - in 625 (72.28%), and the mixed - in 32 (3.81%) patients. Dysplasia of high and low grades was diagnosed in 32 (3.81%) (95% CІ 2.04 – 4.62), including: in 24 (75.0%) - low, and in 8 (25.0%) – high. Аdenocarcinoma was revealed in 4 (0.47%) patients (95% CІ 0.20 – 1.36). Conclusion. Мorphological verdict constitutes the main and objective criterion for the BE verification, what is important for selection of the treatment tactics and certainly help to determine the disease prognosis.