The Emerging Role of ncRNAs and RNA-Binding Proteins in Mitotic Apparatus Formation

The Emerging Role of ncRNAs and RNA-Binding Proteins in Mitotic Apparatus Formation

Mounting experimental evidence shows that non-coding RNAs (ncRNAs) serve a wide variety of biological functions. Recent studies suggest that a part of ncRNAs are critically important for supporting the structure of subcellular architectures. Here, we summarize the current literature demonstrating th...

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Veröffentlicht in:Non-coding RNA 2020-03, Vol.6 (1), p.13
Hauptverfasser: Ito, Kei K, Watanabe, Koki, Kitagawa, Daiju
Format: Artikel
Sprache:eng
Schlagworte:
Binding proteins
centrosome
Genetic aspects
kinetochore
Methods
Mitosis
mitotic spindle
ncrna
Physiological aspects
Review
RNA sequencing
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Beschreibung
Zusammenfassung:Mounting experimental evidence shows that non-coding RNAs (ncRNAs) serve a wide variety of biological functions. Recent studies suggest that a part of ncRNAs are critically important for supporting the structure of subcellular architectures. Here, we summarize the current literature demonstrating the role of ncRNAs and RNA-binding proteins in regulating the assembly of mitotic apparatus, especially focusing on centrosomes, kinetochores, and mitotic spindles.
ISSN:2311-553X
2311-553X
DOI:10.3390/ncrna6010013