Impact of increasing alanine aminotransferase levels within normal range on incident diabetes

Background/Purpose Abnormal alanine aminotransferase level (ALT) levels might be associated with type 2 diabetes, but whether higher ALT levels within the normal range predict the risk is unknown. Methods We followed a community-based cohort of 3446 individuals who were ≥35 years old without diabete...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of the Formosan Medical Association 2012-04, Vol.111 (4), p.201-208
Hauptverfasser:	Wang, Chong-Shan, Chang, Ting-Tsung, Yao, Wei-Jen, Wang, Shan-Tair, Chou, Pesus
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Aged alanine aminotransferase Alanine Transaminase - blood Body Mass Index Case-Control Studies Cohort Studies cohort study Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - epidemiology Female Follow-Up Studies Glucose Tolerance Test Humans Incidence incident type 2 diabetes Internal Medicine Male Middle Aged Proportional Hazards Models Reference Values Risk Factors Socioeconomic Factors Surveys and Questionnaires Taiwan - epidemiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Background/Purpose Abnormal alanine aminotransferase level (ALT) levels might be associated with type 2 diabetes, but whether higher ALT levels within the normal range predict the risk is unknown. Methods We followed a community-based cohort of 3446 individuals who were ≥35 years old without diabetes and hepatitis B or C in southern Taiwan for 8 years (1997–2004) to study the risk for type 2 diabetes with different normal ALT levels. Results Among the 337 incident diabetes cases, 16.0% were from those with ALT levels
ISSN:	0929-6646
DOI:	10.1016/j.jfma.2011.04.004