Prevalence and impact of Sjögren's syndrome in primary biliary cholangitis: a systematic review and meta-analysis

Prevalence and impact of Sjögren's syndrome in primary biliary cholangitis: a systematic review and meta-analysis

We performed a systematic review and meta-analysis to evaluate the prevalence of concomitant Sjögren's syndrome (SS) with primary biliary cholangitis (PBC) in adults and quantify the impact of SS on PBC. PubMed, Web of Science and Cochrane library were searched using subject terms and predefine...

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Veröffentlicht in:Annals of hepatology 2022-11, Vol.27 (6), p.100746-100746, Article 100746
Hauptverfasser: Deng, Xiaoling, Li, Jiahuan, Hou, Shuhui, Ci, Bai, Liu, Beibei, Xu, Keshu
Format: Artikel
Sprache:eng
Schlagworte:
Autoimmune disease
Biochemical characteristics
Immunological indexes
Overlap syndrome
Prevalence
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Zusammenfassung:We performed a systematic review and meta-analysis to evaluate the prevalence of concomitant Sjögren's syndrome (SS) with primary biliary cholangitis (PBC) in adults and quantify the impact of SS on PBC. PubMed, Web of Science and Cochrane library were searched using subject terms and predefined inclusion and exclusion criteria. Seventeen articles were included. The prevalence of SS in PBC patients ranged from 3.5 to 73% (35% pooled) (95% CI: 28–41%; p 
ISSN:1665-2681
2659-5982
DOI:10.1016/j.aohep.2022.100746