Severe Disseminated Infection with Emerging Lineage of Methicillin-Sensitive Staphylococcus aureus

We report a case of severe disseminated infection in an immunocompetent man caused by an emerging lineage of methicillin-sensitive Staphylococcus aureus clonal complex 398. Genes encoding classic virulence factors were absent. The patient made a slow recovery after multiple surgical interventions an...

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Veröffentlicht in:	Emerging infectious diseases 2019-01, Vol.25 (1), p.187-189
Hauptverfasser:	Jewell, Paul, Dixon, Luke, Singanayagam, Aran, Ghani, Rohma, Wong, Ernie, Coleman, Meg, Pichon, Bruno, Kearns, Angela, Russell, Georgina, Hatcher, James
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intravenous Anti-Bacterial Agents - administration & dosage Antimicrobial resistance bacterial infection Care and treatment Case studies Development and progression epidural abscess Floxacillin - administration & dosage flucloxacillin Genes Humans Immunocompetence Immunocompromised host Infection Livestock Magnetic Resonance Imaging Male Methicillin - pharmacology methicillin-resistant Staphylococcus aureus methicillin-sensitive Staphylococcus aureus Middle Aged Public health Research Letter Severe Disseminated Infection with Emerging Lineage of Methicillin-Sensitive Staphylococcal infections Staphylococcal Infections - diagnostic imaging Staphylococcal Infections - drug therapy Staphylococcal Infections - microbiology Staphylococcal Infections - surgery Staphylococcus aureus Staphylococcus aureus - drug effects Staphylococcus aureus - isolation & purification Staphylococcus aureus infections Therapeutics Tomography, X-Ray Computed Treatment Outcome Virulence (Microbiology) Whole Genome Sequencing
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Zusammenfassung:	We report a case of severe disseminated infection in an immunocompetent man caused by an emerging lineage of methicillin-sensitive Staphylococcus aureus clonal complex 398. Genes encoding classic virulence factors were absent. The patient made a slow recovery after multiple surgical interventions and a protracted course of intravenous flucloxacillin.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2501.180684