Genomic Survey of Bordetella pertussis Diversity, United States, 2000-2013

We characterized 170 complete genome assemblies from clinical Bordetella pertussis isolates representing geographic and temporal diversity in the United States. These data capture genotypic shifts, including increased pertactin deficiency, occurring amid the current pertussis disease resurgence and...

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Veröffentlicht in:	Emerging infectious diseases 2019-04, Vol.25 (4), p.780-783
Hauptverfasser:	Weigand, Michael R, Williams, Margaret M, Peng, Yanhui, Kania, Dane, Pawloski, Lucia C, Tondella, Maria L
Format:	Artikel
Sprache:	eng
Schlagworte:	bacteria Bordetella pertussis Bordetella pertussis - classification Bordetella pertussis - genetics Data collection Dispatch Diversity, United States, 2000–2013 Genetic Variation Genome, Bacterial Genomes Genomic Survey of Genomics Genomics - methods Geography, Medical History, 21st Century Humans Immune response Lectins pertussis Phylogeny Polymorphism, Single Nucleotide Proteins Public health Public Health Surveillance United States United States - epidemiology Vaccines whooping cough Whooping Cough - epidemiology Whooping Cough - history Whooping Cough - microbiology
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Zusammenfassung:	We characterized 170 complete genome assemblies from clinical Bordetella pertussis isolates representing geographic and temporal diversity in the United States. These data capture genotypic shifts, including increased pertactin deficiency, occurring amid the current pertussis disease resurgence and provide a foundation for needed research to direct future public health control strategies.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2504.180812