mSphere of Influence: Metabolic redundancies enhance pathogenesis

McKenzie Lehman works in the field of bacterial pathogenesis and metabolism. In this mSphere of Influence article, she reflects on how three papers entitled "Glycolytic dependency of high-level nitric oxide resistance and virulence in by N. P. Vitko, N. A. Spahich, and A. R. Richardson (mBio 6:...

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Veröffentlicht in:	mSphere 2024-07, Vol.9 (7), p.e0023924
1. Verfasser:	Lehman, McKenzie K
Format:	Artikel
Sprache:	eng
Schlagworte:	amino acid transport Bacteriology Commentary Glucose Glycolysis Humans Metabolism Metabolites Nitric oxide Pathogenesis Pathogens Skin Staphylococcal Infections - microbiology Staphylococcus aureus Staphylococcus aureus - genetics Staphylococcus aureus - metabolism Staphylococcus aureus - pathogenicity Staphylococcus infections Sulfur Virulence
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Zusammenfassung:	McKenzie Lehman works in the field of bacterial pathogenesis and metabolism. In this mSphere of Influence article, she reflects on how three papers entitled "Glycolytic dependency of high-level nitric oxide resistance and virulence in by N. P. Vitko, N. A. Spahich, and A. R. Richardson (mBio 6:e00045-15, 2015, https://doi.org/10.1128/mbio.00045-15), "The cystine transporters TcyABC and TcyP facilitate nutrient sulfur acquisition during infection" by J. M. Lensmire, J. P. Dodson, B. Y. Hsueh, M. R. Wischer, et al. (Infect Immun 88:e00690-19, 2020, https://doi.org/10.1128/iai.00690-19), and "The second messenger c-di-AMP inhibits the osmolyte uptake system OpuC in " by C. F. Schuster, L. E. Bellows, T. Tosi, I. Campeotto, et al. (Sci Signal 16:ra81, 2016, https://doi.org/10.1126/scisignal.aaf7279) impacted her work on bacterial metabolism and pathogenesis.
ISSN:	2379-5042 2379-5042
DOI:	10.1128/msphere.00239-24