Dielectrophoretic Particle Chromatography: From Batch Processing to Semi-Continuous High-Throughput Separation

The development of highly selective separation processes is a focus of current research. In 2016, the German Science Foundation funded a priority program SPP 2045 “MehrDimPart—highly specific multidimensional fractionation of fine particles with technical relevance” that aims to develop new or enhan...

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Veröffentlicht in:Powders 2024-02, Vol.3 (1), p.54-64
Hauptverfasser: Giesler, Jasper, Weirauch, Laura, Thöming, Jorg, Pesch, Georg R., Baune, Michael
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Sprache:eng
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Zusammenfassung:The development of highly selective separation processes is a focus of current research. In 2016, the German Science Foundation funded a priority program SPP 2045 “MehrDimPart—highly specific multidimensional fractionation of fine particles with technical relevance” that aims to develop new or enhance existing approaches for the separation of nano- and micrometer-sized particles. Dielectrophoretic separators achieve highly selective separations of (bio-)particles in microfluidic devices or can handle large quantities when non-selective separation is sufficient. Recently, separator designs were developed that aim to combine a high throughput and high selectivity. Here, we summarize the development from a microfluidic fast chromatographic separation via frequency modulated dielectrophoretic particle chromatography (DPC) toward a macrofluidic high throughput separation. Further, we provide a starting point for future work by providing new experimental data demonstrating for the first time the trapping of 200 nm polystyrene particles in a dielectrophoretic high-throughput separator that uses printed circuit boards as alternatives for expensive electrode arrays.
ISSN:2674-0516
2674-0516
DOI:10.3390/powders3010005