Treatment Failure of Dihydroartemisinin/Piperaquine for Plasmodium falciparum Malaria, Vietnam

We conducted a study in Binh Phuoc, Vietnam, in 2015 on the therapeutic efficacy of dihydroartemisinin/piperaquine for Plasmodium falciparum malaria. A high number of treatment failures (14/40) was found, and piperaquine resistance in Vietnam was confirmed. A change in the malaria treatment policy f...

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Veröffentlicht in:	Emerging infectious diseases 2017-04, Vol.23 (4), p.715-717
Hauptverfasser:	Phuc, Bui Quang, Rasmussen, Charlotte, Duong, Tran Thanh, Dong, Le Than, Loi, Mai Anh, Ménard, Didier, Tarning, Joel, Bustos, Dorina, Ringwald, Pascal, Galappaththy, Gawrie Loku, Thieu, Nguyen Quang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Antimalarials - administration & dosage Antimalarials - therapeutic use artemisinin Artemisinins - administration & dosage Artemisinins - therapeutic use Care and treatment dihydroartemisinin-piperaquine Drug Combinations Drug Resistance Female Humans Malaria Malaria, Falciparum - drug therapy Malaria, Falciparum - epidemiology Malaria, Vietnam Male Medical research Middle Aged Mutation Plasmodium falciparum Plasmodium falciparum - genetics Protozoan Proteins - genetics Protozoan Proteins - metabolism Quinolines - administration & dosage Quinolines - therapeutic use Research Letter Treatment Failure of Dihydroartemisinin/Piperaquine for Vietnam Vietnam - epidemiology
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Beschreibung
Zusammenfassung:	We conducted a study in Binh Phuoc, Vietnam, in 2015 on the therapeutic efficacy of dihydroartemisinin/piperaquine for Plasmodium falciparum malaria. A high number of treatment failures (14/40) was found, and piperaquine resistance in Vietnam was confirmed. A change in the malaria treatment policy for Vietnam is in process.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2304.161872