Assessment of Microbiological Environment and the Level of Antibiotic Resistance in a Multidisciplinary Hospital

The objective : to determine the incidence and drug sensitivity of the main pathogens causing community-acquired and nosocomial infections in patients staying in a multidisciplinary hospital. Subjects and Methods : a retrospective study of the microbiological population in patients of a multidisciplinary hospital was carried out. The period over 3 years was assessed. 3,954 samples of biological materials from various sites were studied. Results : gram-positive bacteria prevailed in the general structure of microbial environment of patients – Staphylococcus aureus (28%), and Enterococcus faecalis (10%), as well as gram-negative – Escherichia coli (26%), and Klebsiella pneumoniae (13%). The majority of non-fermenting gram-negative microorganisms isolated from patients in the intensive care unit demonstrated multiple resistance and quantitatively prevailed over those in surgery units. The spectrum of antibiotic susceptibility of microorganisms of the same species isolated from patients of therapy and surgery departments differed.