Robustly federated learning model for identifying high-risk patients with postoperative gastric cancer recurrence

The prediction of patient disease risk via computed tomography (CT) images and artificial intelligence techniques shows great potential. However, training a robust artificial intelligence model typically requires large-scale data support. In practice, the collection of medical data faces obstacles r...

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Veröffentlicht in:Nature communications 2024-01, Vol.15 (1), p.742-11, Article 742
Hauptverfasser: Feng, Bao, Shi, Jiangfeng, Huang, Liebin, Yang, Zhiqi, Feng, Shi-Ting, Li, Jianpeng, Chen, Qinxian, Xue, Huimin, Chen, Xiangguang, Wan, Cuixia, Hu, Qinghui, Cui, Enming, Chen, Yehang, Long, Wansheng
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Sprache:eng
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Zusammenfassung:The prediction of patient disease risk via computed tomography (CT) images and artificial intelligence techniques shows great potential. However, training a robust artificial intelligence model typically requires large-scale data support. In practice, the collection of medical data faces obstacles related to privacy protection. Therefore, the present study aims to establish a robust federated learning model to overcome the data island problem and identify high-risk patients with postoperative gastric cancer recurrence in a multicentre, cross-institution setting, thereby enabling robust treatment with significant value. In the present study, we collect data from four independent medical institutions for experimentation. The robust federated learning model algorithm yields area under the receiver operating characteristic curve (AUC) values of 0.710, 0.798, 0.809, and 0.869 across four data centres. Additionally, the effectiveness of the algorithm is evaluated, and both adaptive and common features are identified through analysis. Medical data faces isolation and cross-center performance issues. Here, the authors propose a robust federated learning model to identify high-risk postoperative gastric cancer recurrence, achieving promising results across data from four independent medical institutions.
ISSN:2041-1723
2041-1723
DOI:10.1038/s41467-024-44946-4