Antioxidant effect of vitamin D-3 and its relation to salivary protein and oral health

Aims: To investigate the antioxidant effects of vitamin D3 on oral health and to evaluate its effect on total salivary proteins in saliva. Materials and Methods: Forty patients were classified into two groups: Group 1: (20) chronic gingivitis patients, did not receive vitamin D3 (control group), Group 2: (20) chronic gingivitis patients (treatment group), received Vitamin D3 1000IU capsule. Scaling and polishing have been carried out for each volunteer to reach the base line for plaque index, gingival index, oral hygiene index and calculus index. In the next day, these indices were measured for all participants, then measured after 3 weeks then after 6 weeks from treatment. At the same visits, five milliliters of unstimulated saliva were collected for measurement of total salivary proteins and total antioxidant capacity. Results: there were significant reduction in oral health indices in 21st and 42nd days of the study which mean good response to treatment and improvement in gingival health. Conclusion: Vitamin D3 can be a good adjuvant in periodontal therapy