Fatal coxsackievirus A-16 pneumonitis in adult

Coxsackievirus A-16 (CVA-16) is the agent of hand, foot, and mouth disease in children. We report a case of fatal pneumonitis in an adult due to a CVA-16 strain with a low (78.6%) rate of sequence homology with the reference strain. A modified, more virulent, strain of CVA-16 could be emerging.

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Bibliographische Detailangaben
Veröffentlicht in:	Emerging infectious diseases 2007-07, Vol.13 (7), p.1084-1086
Hauptverfasser:	Legay, François, Lévêque, Nicolas, Gacouin, Arnaud, Tattevin, Pierre, Bouet, Julien, Thomas, Rémi, Chomelt, Jean-Jacques
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Bacterial pneumonia Children Coxsackievirus coxsackievirus A-16 Coxsackievirus Infections - diagnosis Coxsackievirus Infections - virology Diseases Dispatch enterovirus Enterovirus A, Human - classification Enterovirus A, Human - isolation & purification Fatal Outcome foot France hand Hand, Foot and Mouth Disease - diagnosis Hand, Foot and Mouth Disease - virology Health aspects Humans Male Phylogeny Pneumonia Pneumonia, Viral - diagnosis Pneumonia, Viral - virology pneumonitis Polymerase Chain Reaction
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Beschreibung
Zusammenfassung:	Coxsackievirus A-16 (CVA-16) is the agent of hand, foot, and mouth disease in children. We report a case of fatal pneumonitis in an adult due to a CVA-16 strain with a low (78.6%) rate of sequence homology with the reference strain. A modified, more virulent, strain of CVA-16 could be emerging.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid1307.070295