Diabetes mellitus and COVID-19: A bidirectional relationship?

The COVID-19 pandemic has generated a public health emergency around the world. The risk, severity, and mortality of the disease has been associated to chronic diseases, such as diabetes mellitus. There are multiple pathophysiological explanations that relate these two entities. The possibility of a bidirectional relationship between COVID-19 and diabetes mellitus type 1 and 2 has been raised. Most studies agree that diabetes mellitus of any etiology is associated with a negative outcome of the infection. Also, CO-VID-19 can cause a worsening of glycemic control and can be a trigger for the development of diabetes mellitus type 1.