Generation and characterization of induced pluripotent stem (iPS) cell line (SDUCTi001-A) using fibroblasts derived from male-healthy donor

Generation and characterization of induced pluripotent stem (iPS) cell line (SDUCTi001-A) using fibroblasts derived from male-healthy donor

Induced pluripotent stem (iPS) cell lines have wide valuable applications in experimental research, including developmental, pathological, and drug screening studies. Using integration-free episomal plasmids, we have generated a new iPS cell line from a 26-year-old healthy male donor. Characterizati...

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Veröffentlicht in:Stem cell research 2022-12, Vol.65, p.102961, Article 102961
Hauptverfasser: Kamand, Morad, Hohmann, Sonja, Louise Forsberg, Sheena, Thomassen, Mads, Ilieva, Mirolyuba, Fex Svenningsen, Åsa, Meyer, Morten, Maria Michel, Tanja
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Cell Line
Humans
Male
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Zusammenfassung:Induced pluripotent stem (iPS) cell lines have wide valuable applications in experimental research, including developmental, pathological, and drug screening studies. Using integration-free episomal plasmids, we have generated a new iPS cell line from a 26-year-old healthy male donor. Characterization of the established cell line confirmed the expression of pluripotency markers, differentiation into the three germ layers, and absence of chromosomal abnormalities.
ISSN:1873-5061
1876-7753
DOI:10.1016/j.scr.2022.102961