Essential tremor plus affects disease prognosis: A longitudinal study

Linear logistic regression analysis was used to investigate the predictive factors affecting the annual progress rate of scores on various scales. A total of 541 ET patients, including 267 (49.4%) pure ET patients and 274 (50.6%) ET-plus patients, were recruited, of whom 22 were lost to follow-up due to refusal or incorrect contact information (dropout rate: 4.1%), and 7 patients passed away. [...]461 successfully completed face-to-face follow-up [Figure 1], among whom 218 (47.3%) and 243 (52.7%) were initially diagnosed with pure ET and ET-plus, with average follow-up intervals of 23.29 ± 5.98 and 21.83 ± 5.47 months, respectively. A strong negative association was found between the baseline and annual increase in TETRAS-II scores (β = −0.054, 95% CI = −0.074 to −0.034, P