Repeated COVID-19 relapse during post-discharge surveillance with viral shedding lasting for 67 days in a recovered patient infected with SARS-CoV-2

A case who revealed the longest duration of viral shedding (67 days) in current reports, presented complicated characteristic on the relapse of COVID-19 due to the inconsistent performance of chest radiography and SARS-CoV-2-RNA detection after discharge. Lopinavir-interferon α2b boosted ribavirin f...

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Veröffentlicht in:	Journal of microbiology, immunology and infection immunology and infection, 2021-02, Vol.54 (1), p.101-104
Hauptverfasser:	Liu, Fang, Cai, Zhao-bin, Huang, Jin-song, Niu, Hai-ying, Yu, Wen-yan, Zhang, Yan, Yan, Ting-bo, Chen, Chen, Liu, Yuan, Xu, Ai-fang
Format:	Artikel
Sprache:	eng
Schlagworte:	Aftercare Coronavirus disease 2019 COVID-19 - diagnostic imaging COVID-19 - drug therapy COVID-19 - physiopathology COVID-19 - virology Female Hospitalization Humans Lopinavir - therapeutic use Middle Aged Patient Discharge Prognosis Recovered patients Recurrence Ribavirin - therapeutic use RNA, Viral - genetics RNA, Viral - isolation & purification SARS-CoV-2 - genetics SARS-CoV-2 - physiology SARS-CoV-2 re-positive Short Communication Thorax - diagnostic imaging Viral shedding Virus Shedding - drug effects
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Zusammenfassung:	A case who revealed the longest duration of viral shedding (67 days) in current reports, presented complicated characteristic on the relapse of COVID-19 due to the inconsistent performance of chest radiography and SARS-CoV-2-RNA detection after discharge. Lopinavir-interferon α2b boosted ribavirin following with lopinavir boosted budesonide might be a potent treatment for viral clearance.
ISSN:	1684-1182 1995-9133
DOI:	10.1016/j.jmii.2020.07.017