Pathogenesis of hepatitis C during pregnancy and childhood

Pathogenesis of hepatitis C during pregnancy and childhood

The worldwide prevalence of HCV infection is between 1% and 8% in pregnant women and between 0.05% and 5% in children. Yet the pathogenesis of hepatitis C during pregnancy and in the neonatal period remains poorly understood. Mother-to-child transmission (MTCT), a leading cause of pediatric HCV infe...

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Veröffentlicht in:Viruses 2012-12, Vol.4 (12), p.3531-3550
Hauptverfasser: Le Campion, Armelle, Larouche, Ariane, Fauteux-Daniel, Sébastien, Soudeyns, Hugo
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Child
Child, Preschool
Coinfection
Female
Hepacivirus - pathogenicity
Hepatitis C
Hepatitis C - pathology
Hepatitis C - transmission
Hepatitis C - virology
Hepatitis C virus
HIV Infections - complications
Humans
Infant
Infant, Newborn
Infectious Disease Transmission, Vertical
mother-to-child transmission
pathogenesis
pediatrics
Pregnancy
Pregnancy Complications, Infectious - pathology
Pregnancy Complications, Infectious - virology
Review
Risk Factors
Viral Load
Young Adult
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Zusammenfassung:The worldwide prevalence of HCV infection is between 1% and 8% in pregnant women and between 0.05% and 5% in children. Yet the pathogenesis of hepatitis C during pregnancy and in the neonatal period remains poorly understood. Mother-to-child transmission (MTCT), a leading cause of pediatric HCV infection, takes place at a rate of
ISSN:1999-4915
1999-4915
DOI:10.3390/v4123531