Analysis of the predictive factors for a critical illness of COVID-19 during treatment － relationship between serum zinc level and critical illness of COVID-19

•A close relationship is found between low serum zinc and severe states of COVID-19.•Hypozincemia critically contributes to the aggravation of COVID-19.•Serum zinc level can be a predictive factor for a critical illness of COVID-19.•We would recommend oral medication of zinc salts to patients with C...

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Veröffentlicht in:	International journal of infectious diseases 2020-11, Vol.100, p.230-236
Hauptverfasser:	Yasui, Yukako, Yasui, Hiroyuki, Suzuki, Kumiko, Saitou, Takako, Yamamoto, Yoshiki, Ishizaka, Toshihiko, Nishida, Kouji, Yoshihara, Shingo, Gohma, Iwao, Ogawa, Yoshihiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Cohort Studies COVID-19 COVID-19 - blood COVID-19 - epidemiology COVID-19 - physiopathology Critical illness Critical Illness - epidemiology Female Humans Japan Logistic regression analysis Male Middle Aged Pandemics Patient Acuity Predictive factors Predictive Value of Tests Risk Factors ROC Curve SARS-CoV-2 Serum zinc Zinc - blood
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Zusammenfassung:	•A close relationship is found between low serum zinc and severe states of COVID-19.•Hypozincemia critically contributes to the aggravation of COVID-19.•Serum zinc level can be a predictive factor for a critical illness of COVID-19.•We would recommend oral medication of zinc salts to patients with COVID-19. Because most severely ill patients with COVID-19 in our hospital showed zinc deficiency, we aimed to examine the relationship between the patient’s serum zinc level and severe cases of COVID-19. Serum zinc
ISSN:	1201-9712 1878-3511
DOI:	10.1016/j.ijid.2020.09.008