Extraction, Component Analysis and Biological Activity Evaluation of Total Flavonoids from Phellinus igniarius

In order to study the extraction technology of total flavonoids from Phellinus igniarius systematically, clarify the composition and content of flavonoids in total flavonoids, and explore the biological activity of total flavonoids from Phellinus igniarius. The extraction technology of Phellinus igniarius total flavonoids was optimized by response surface method, the composition of Phellinus igniarius total flavonoids was analyzed, and some of its biological activities were also detected. The results showed that the optimal extraction conditions were extraction temperature of 73 ℃, solid-liquid ratio of 1:50 g/mL and extraction time of 3 h, under which the yield of Phellinus igniarius total flavonoids reached 2.68%. The types and contents of flavonoids in Phellinus igniarius total flavonoids were determined by HPLC. Total flavonoids of Phellinus igniarius mainly contained taxifolin, quercetin and kaempferol, and the content of taxifolin was 3727.31 mg/kg. The analysis of biological activities of Phellinus ign