Thrombocytopenia as a Bleeding Risk Factor in Atrial Fibrillation and Coronary Artery Disease: Insights From the AFIRE Study

Background Thrombocytopenia poses a risk of bleeding in patients with chronic coronary syndrome after coronary intervention. However, whether thrombocytopenia also increases the bleeding risk in patients with atrial fibrillation and chronic coronary syndrome remains unclear. Methods and Results This...

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Veröffentlicht in:	Journal of the American Heart Association 2023-10, Vol.12 (20), p.e031096-e031096
Hauptverfasser:	Iijima, Raisuke, Tokue, Masahide, Nakamura, Masato, Yasuda, Satoshi, Kaikita, Koichi, Akao, Masaharu, Ako, Junya, Matoba, Tetsuya, Miyauchi, Katsumi, Hagiwara, Nobuhisa, Kimura, Kazuo, Hirayama, Atsushi, Matsui, Kunihiko, Ogawa, Hisao
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticoagulants - adverse effects atrial fibrillation Atrial Fibrillation - complications Atrial Fibrillation - drug therapy Atrial Fibrillation - epidemiology chronic coronary syndrome Coronary Artery Disease - complications Coronary Artery Disease - drug therapy Coronary Artery Disease - epidemiology Hemorrhage - chemically induced Hemorrhage - epidemiology Humans Original Research Percutaneous Coronary Intervention - adverse effects Platelet Aggregation Inhibitors - adverse effects Risk Factors Rivaroxaban - adverse effects thrombocytopenia Thrombocytopenia - complications Thrombocytopenia - epidemiology Treatment Outcome
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Zusammenfassung:	Background Thrombocytopenia poses a risk of bleeding in patients with chronic coronary syndrome after coronary intervention. However, whether thrombocytopenia also increases the bleeding risk in patients with atrial fibrillation and chronic coronary syndrome remains unclear. Methods and Results This study evaluated the AFIRE (Atrial Fibrillation and Ischemic Events With Rivaroxaban in Patients With Stable Coronary Artery Disease) trial. Thrombocytopenia was defined as platelet count
ISSN:	2047-9980 2047-9980
DOI:	10.1161/JAHA.123.031096