Epidemiology and secular trends of malignant lymphoma in Japan: Analysis of 9426 cases according to the World Health Organization classification

This study provides an overview of the epidemiology and secular trends of malignant lymphoma in Japan. Using data from clinics and hospitals throughout Japan, we analyzed 9426 cases of malignant lymphoma diagnosed in 2007‐2014. We show that the proportion of follicular lymphoma and methotrexate‐asso...

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Veröffentlicht in:	Cancer medicine (Malden, MA) MA), 2018-11, Vol.7 (11), p.5843-5858
Hauptverfasser:	Muto, Reiji, Miyoshi, Hiroaki, Sato, Kensaku, Furuta, Takuya, Muta, Hiroko, Kawamoto, Keisuke, Yanagida, Eriko, Yamada, Kyohei, Ohshima, Koichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult adult T‐cell leukemia/lymphoma Age Age of Onset Aged Aged, 80 and over Cancer Prevention diffuse large B‐cell lymphoma Epidemiology Female follicular lymphoma Humans Japan Japan - epidemiology Lymphocytes Lymphocytes B Lymphoma Lymphoma - chemically induced Lymphoma - classification Lymphoma - epidemiology Male Methotrexate Methotrexate - adverse effects Middle Aged Original Research Sex Factors Trends
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Zusammenfassung:	This study provides an overview of the epidemiology and secular trends of malignant lymphoma in Japan. Using data from clinics and hospitals throughout Japan, we analyzed 9426 cases of malignant lymphoma diagnosed in 2007‐2014. We show that the proportion of follicular lymphoma and methotrexate‐associated lymphoproliferative disorder increased during this time, as did the onset age for follicular lymphoma and diffuse large B‐cell lymphoma. Significant increases in onset age for follicular lymphoma and diffuse large B‐cell lymphoma were observed in both men and women (all P values
ISSN:	2045-7634 2045-7634
DOI:	10.1002/cam4.1805