Phytotoxic and Antifungal Metabolites from Curvularia crepinii QTYC-1 Isolated from the Gut of Pantala flavescens

Four metabolites ( ⁻ ), including a new macrolide, -demethylated-zeaenol ( ), and three known compounds, zeaenol ( ), adenosine ( ), and ergosta-5,7,22-trien-3b-ol ( ) were isolated and purified from QTYC-1, a fungus residing in the gut of . The structures of isolated compounds were identified on the basis of extensive spectroscopic analysis and by comparison of the corresponding data with those reported in the literature previously. The new compound showed good phytotoxic activity against with an IC value of less than 5 µg/mL, which was comparable to that of positive 2,4-dichlorophenoxyacetic acid (2,4-D). Compound exhibited moderate herbicidal activity against with an IC value of 28.8 μg/mL. Furthermore, the new metabolite was found to possess moderate antifungal activity against at the concentration of 100 µg/mL, with the inhibition rate of 50%. These results suggest that the new macrolide and the known compound have potential to be used as biocontrol agents in agriculture.