A Facile Synthesis of Polysubstituted Pyrroles by One‐Pot Three‐Component Reaction
A new and efficient one‐pot synthesis of polysubstituted pyrrole derivatives by three‐component reaction between dialkyl acetylenedicarboxylates, triphenylphosphine, 2‐aminopyridin derivatives in the presence of arylglyoxals is described. The reactions were performed in dichloromethane at room tempe...
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| Veröffentlicht in: | E-journal of chemistry 2012-01, Vol.9 (4), p.2239-2244 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | A new and efficient one‐pot synthesis of polysubstituted pyrrole derivatives by three‐component reaction between dialkyl acetylenedicarboxylates, triphenylphosphine, 2‐aminopyridin derivatives in the presence of arylglyoxals is described. The reactions were performed in dichloromethane at room temperature and neutral conditions and afforded high yields of products. |
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| ISSN: | 2090-9063 0973-4945 2090-9071 2090-9810 |
| DOI: | 10.1155/2012/915861 |