Bioadhesive Nanoparticles for Local Drug Delivery

Local drug delivery is an effective strategy for achieving direct and instant therapeutic effects. Current clinical treatments have fallen short and are limited by traditional technologies. Bioadhesive nanoparticles (NPs), however, may be a promising carrier for optimized local drug delivery, offeri...

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Veröffentlicht in:International journal of molecular sciences 2022-02, Vol.23 (4), p.2370
Hauptverfasser: Yu, Liu, Luo, Zewen, Chen, Tian, Ouyang, Yaqi, Xiao, Lingyun, Liang, Shu, Peng, Zhangwen, Liu, Yang, Deng, Yang
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Sprache:eng
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Zusammenfassung:Local drug delivery is an effective strategy for achieving direct and instant therapeutic effects. Current clinical treatments have fallen short and are limited by traditional technologies. Bioadhesive nanoparticles (NPs), however, may be a promising carrier for optimized local drug delivery, offering prolonged drug retention time and steadily maintained therapeutic concentrations. In addition, the possibility of clinical applications of this platform are abundant, as most polymers used for bioadhesion are both biodegradable and biocompatible. This review highlights the major advances in the investigations of polymer-based bioadhesive nanoparticles and their innumerable applications in local drug delivery.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms23042370