Biocompatible synthesis of reduced graphene oxide from Euphorbia heterophylla (L.) and their in-vitro cytotoxicity against human cancer cell lines

[Display omitted] •A simple and facile biocompatible method for the reduction of graphene oxide (GO).•Reduction of graphene oxide (rGO) from leaves extract of Euphorbia heterophylla (L.).•The rGO shows significant cytotoxicity on A549- Human Lung Cancer cell line and HepG2-Human Hepatocarcinomatous Cell lines.•Green synthesis of rGO is very easy, in expensive, cheap, non-toxic, biocompatibility and ecofriendly. Facile and biocompatible synthesis of reduced graphene oxide from graphene oxide as a precursor and aqueous leaves extract of Euphorbia heterophylla (L.), act as a reducing /capping /stabilizing agent by green chemistry approaches. The obtained product was analyzed by Ultraviolet-Visible spectroscopy (UV–vis), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), Raman spectroscopy and Scanning electron Microscopy (SEM). In addition to this, the significant cytotoxicity of rGO studied against cancerous cell lines such as A549- Human Lung cancer cell line and HepG2-Human Hepatocarcinoma Cell lines in-vitro. These results indicate that the biocompatible synthesis of rGO is straightforward, inexpensive and environmentally friendly for promising large-scale production of industrial purpose and then finding further biomedical applications.