Clinical and Financial Benefits of Intra-Articular Tranexamic Acid in Total Knee Arthroplasty

Purpose. To determine whether intra-articular tranexamic acid (TXA) use after total knee arthroplasty (TKA) results in decreased postoperative blood transfusion and length of hospital stay. Methods. Medical records of 1981 patients (mean age, 69.2 years) who underwent primary TKA with (n=1006) or wi...

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Veröffentlicht in:	Journal of orthopaedic surgery (Hong Kong) 2016-04, Vol.24 (1), p.3-6
Hauptverfasser:	Goyal, Navendu, Chen, Darren B, Harris, Ian A, Rowden, Neville, Kirsh, George, MacDessi, Samuel J
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antifibrinolytic agents Antifibrinolytic Agents - administration & dosage Arthroplasty, Replacement, Knee Blood Transfusion Blood transfusions Cost control Cost Savings Female Hospitals Humans Injections, Intra-Articular Joint Diseases - surgery Joint replacement surgery Joint surgery Knee Length of Stay Male Middle Aged Molecular weight Patients Postoperative Care Retrospective Studies Thrombosis Tranexamic Acid - administration & dosage
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Zusammenfassung:	Purpose. To determine whether intra-articular tranexamic acid (TXA) use after total knee arthroplasty (TKA) results in decreased postoperative blood transfusion and length of hospital stay. Methods. Medical records of 1981 patients (mean age, 69.2 years) who underwent primary TKA with (n=1006) or without (n=975) TXA use by any of 4 knee arthroplasty surgeons were reviewed. TXA (3000 mg/30ml) was administered via an epidural catheter into the knee joint after wound closure. Postoperative blood transfusion was given to patients with haemoglobin (Hb) level
ISSN:	2309-4990 1022-5536 2309-4990
DOI:	10.1177/230949901602400103