Flipper Probes for the Community

This article describes four fluorescent membrane tension probes that have been designed, synthesized, evaluated, commercialized and applied to current biology challenges in the context of the NCCR Chemical Biology. Their names are Flipper-TR®, ER Flipper-TR®, Lyso Flipper-TR®, and Mito Flipper-TR®....

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Veröffentlicht in:	Chimia 2021-12, Vol.75 (12), p.1004-1011
Hauptverfasser:	Assies, Lea, García-Calvo, José, Piazzolla, Francesca, Sanchez, Samantha, Kato, Takehiro, Reymond, Luc, Goujon, Antoine, Colom, Adai, López-Andarias, Javier, Straková, Karolína, Mahecic, Dora, Mercier, Vincent, Riggi, Margot, Jiménez-Rojo, Noemi, Roffay, Chloé, Licari, Giuseppe, Tsemperouli, Maria, Neuhaus, Frederik, Fürstenberg, Alexandre, Vauthey, Eric, Hoogendoorn, Sascha, Gonzalez-Gaitan, Marcos, Zumbuehl, Andreas, Sugihara, Kaori, Gruenberg, Jean, Riezman, Howard, Loewith, Robbie, Manley, Suliana, Roux, Aurelien, Winssinger, Nicolas, Sakai, Naomi, Pitsch, Stefan, Matile, Stefan
Format:	Artikel
Sprache:	eng
Schlagworte:	Coloring Agents Flipper Probes Fluorescence Imaging Fluorescent Dyes Membrane Potential, Mitochondrial Microscopy, Fluorescence NCCR Chemical Biology Ncrr Chemical Biology
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	This article describes four fluorescent membrane tension probes that have been designed, synthesized, evaluated, commercialized and applied to current biology challenges in the context of the NCCR Chemical Biology. Their names are Flipper-TR®, ER Flipper-TR®, Lyso Flipper-TR®, and Mito Flipper-TR®. They are available from Spirochrome.
ISSN:	0009-4293 2673-2424
DOI:	10.2533/chimia.2021.1004