The impact of LABA+ICS fixed combinations on morbidity and economic burden of COPD in Italy: a six-year observational study

Background: In Italy, chronic obstructive pulmonary disease (COPD) has progressively received increasing attention in the last decade, and its impact has been investigated extensively in both clinical and pharmacoeconomic terms. Methods: In 2004, the national health authorities stated the appropriat...

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Veröffentlicht in:	Therapeutic advances in respiratory disease 2011-04, Vol.5 (2), p.83-90
Hauptverfasser:	Dal Negro, Roberto, Bonadiman, Luca, Tognella, Silvia, Micheletto, Claudio, Turco, Paola
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex Hormones - administration & dosage Adrenal Cortex Hormones - economics Adrenergic beta-2 Receptor Agonists - administration & dosage Adrenergic beta-2 Receptor Agonists - economics Aged Chronic obstructive pulmonary disease Drug Therapy, Combination Economics, Pharmaceutical - statistics & numerical data Female Health Expenditures - statistics & numerical data Health Resources - economics Health Resources - utilization Humans Italy - epidemiology Male Middle Aged Morbidity Observational studies Pulmonary Disease, Chronic Obstructive - drug therapy Pulmonary Disease, Chronic Obstructive - economics Pulmonary Disease, Chronic Obstructive - epidemiology Retrospective Studies Severity of Illness Index
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Zusammenfassung:	Background: In Italy, chronic obstructive pulmonary disease (COPD) has progressively received increasing attention in the last decade, and its impact has been investigated extensively in both clinical and pharmacoeconomic terms. Methods: In 2004, the national health authorities stated the appropriateness of long-acting β2 agonists (LABA) and inhaled corticosteroids (ICS) fixed combinations for treating COPD, even though this pharmaceutical option was limited to the severe and very severe stages of the disease (forced expiratory volume in one second [FEV1]
ISSN:	1753-4658 1753-4666 1753-4666
DOI:	10.1177/1753465810386052