In‐depth cardiovascular and pulmonary assessments in children with multisystem inflammatory syndrome after SARS‐CoV‐2 infection: A case series study

In‐depth cardiovascular and pulmonary assessments in children with multisystem inflammatory syndrome after SARS‐CoV‐2 infection: A case series study

We assessed PET‐CT myocardial blood flow (MBF) using N‐13 ammonia, brachial flow‐mediated dilation, and cardiopulmonary exercise test in five post‐discarged MIS‐C survivors. None of the patients (median age: 9, range: 7‐18 years; 3 females; 2 males) had preexisting pediatric chronic conditions. At t...

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Veröffentlicht in:Physiological Reports 2022-03, Vol.10 (5), p.e15201-n/a
Hauptverfasser: Astley, Camilla, Badue Pereira, Maria Fernanda, Lima, Marcos Santos, Buchpiguel, Carlos Alberto, Carneiro, Camila G., Sapienza, Marcelo Tatit, Leal, Gabriela Nunes, Prado, Danilo Marcelo Leite, Peçanha, Tiago, Sieczkowska, Sofia Mendes, Matsuo, Olivia Mari, Lindoso, Livia, Marques, Heloisa Helena, Silva, Clovis Artur, Gualano, Bruno
Format: Artikel
Sprache:eng
Schlagworte:
Adenosine
Ammonia
Anaerobic threshold
Blood flow
Body mass index
Cardiology
cardiovascular imaging
children
Chronic illnesses
Coronaviruses
COVID-19
Diagnosis
Drug dosages
Effusion
Expected values
Females
Heart
Inflammation
Intensive care
Ischemia
Medical research
Medicine, Experimental
MIS‐C
Multisystem inflammatory syndrome in children
Myocardial ischemia
Original
Oxygen therapy
Patients
Pediatrics
Perfusion
Physiology
Severe acute respiratory syndrome
Severe acute respiratory syndrome coronavirus 2
Software
Ultrasonic imaging
Veins & arteries
Ventricle
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Zusammenfassung:We assessed PET‐CT myocardial blood flow (MBF) using N‐13 ammonia, brachial flow‐mediated dilation, and cardiopulmonary exercise test in five post‐discarged MIS‐C survivors. None of the patients (median age: 9, range: 7‐18 years; 3 females; 2 males) had preexisting pediatric chronic conditions. At the follow‐up visit, two patients exhibited severe perfusion defect developed in the left ventricular cavity, suggesting extensive myocardial ischemia (MBF
ISSN:2051-817X
DOI:10.14814/phy2.15201