Natalizumab alters the TCR repertoire after one year of treatment in four MS patients

Natalizumab alters the TCR repertoire after one year of treatment in four MS patients

Discussion/perspectives Given the mechanisms of action of natalizumab, one may hypothesize that the clonal cells observed in the blood after one year of treatment could have a major role in the pathophysiological process in the disease.

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Veröffentlicht in:Journal of Translational Medicine 2011-11, Vol.9 (S2), p.P26-P26, Article P26
Hauptverfasser: Michel, Laure, Salou, Marion, Garcia, Alexandra, Degauque, Nicolas, Salmon, Anne, Ngono, Annie Elong, Nicot, Arnaud, Wiertlewski, Sandrine, Soulillou, Jean-Paul, Brouard, Sophie, Laplaud, David
Format: Artikel
Sprache:eng
Schlagworte:
Immunology
Life Sciences
Medical research
Multiple sclerosis
Poster Presentation
T cell receptors
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Zusammenfassung:Discussion/perspectives Given the mechanisms of action of natalizumab, one may hypothesize that the clonal cells observed in the blood after one year of treatment could have a major role in the pathophysiological process in the disease.
ISSN:1479-5876
1479-5876
DOI:10.1186/1479-5876-9-S2-P26