Botulinum Toxin A for Treatment of Diaphragmatic Myoclonus

To the Editor： Diaphragmatic myoclonus, as a typical unusual focal dyskinesia, is characterized by repetitive involuntary synchronous contractions of the diaphragm and other respiratory muscles. Various clinical presentations and difficulties in identifying etiology might lead to its late diagnoses and ineffective treatment in many cases. Botulinum toxin A has a paralyzing effect on muscles. However, to the best of our knowledge, there have been few reports of injecting botulinum toxin A to the diaphragm. In this case, we reported that diaphragmatic myoclonus was successfully treated by injecting botulinum toxin A into the diaphragm and the rectus abdominis （RA） under needle electromyography （EMG） guidance.