Identification of CDK2-Related Immune Forecast Model and ceRNA in Lung Adenocarcinoma, a Pan-Cancer Analysis

BACKGROUNDTumor microenvironment (TME) plays important roles in different cancers. Our study aimed to identify molecules with significant prognostic values and construct a relevant Nomogram, immune model, competing endogenous RNA (ceRNA) in lung adenocarcinoma (LUAD). METHODS"GEO2R," "...

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Veröffentlicht in:Frontiers in cell and developmental biology 2021-07, Vol.9, p.682002-682002
Hauptverfasser: Liu, Ting-Ting, Li, Rui, Huo, Chen, Li, Jian-Ping, Yao, Jie, Ji, Xiu-li, Qu, Yi-Qing
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Sprache:eng
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Zusammenfassung:BACKGROUNDTumor microenvironment (TME) plays important roles in different cancers. Our study aimed to identify molecules with significant prognostic values and construct a relevant Nomogram, immune model, competing endogenous RNA (ceRNA) in lung adenocarcinoma (LUAD). METHODS"GEO2R," "limma" R packages were used to identify all differentially expressed mRNAs from Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases. Genes with P-value 2 or
ISSN:2296-634X
2296-634X
DOI:10.3389/fcell.2021.682002