Longitudinal Cohort Study of the Association of Triglyceride-glucose Index with Hypertension among Teachers from a University

BackgroundTriglyceride-glucose (TyG) index is regarded as a novel alternative to insulin resistance (IR) , a core pathophysiological mechanism of hypertension. However, it is still controversial about the association of TyG index with hypertension, and relevant longitudinal research is limited.ObjectiveAttempt to examine the association of TyG index with hypertension among teachers from a university.MethodsA retrospective cohort study was conducted from January 2015 to December 2019. Participants (n=602) were teachers from a university who had normal blood pressure and consecutively underwent the annual physical examinations. Their physical examination data were collected, including demographic characteristics, anamnesis, medication history, and biochemical indices in venous blood. The cumulative incidence of hypertension was calculated and compared across groups〔Q1-Q4 (first to fourth quartiles) 〕 of TyG index quartiles. The association of TyG index with hypertension was analyzed, and further analyzed by sex