Association between the triglyceride-glucose index and calcified aortic stenosis in elderly patients: a cross-sectional study

Insulin resistance (IR) is associated with a variety of cardiovascular diseases, but there are few studies on the correlation between IR and calcified aortic stenosis (CAS). In this study, the triglyceride-glucose (TyG) index, which reflects IR, was used to investigate the correlation between IR and...

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Veröffentlicht in:Scientific reports 2023-09, Vol.13 (1), p.14928-8, Article 14928
Hauptverfasser: Hu, Zhihui, Xiong, Tiantian, Chen, Chunling, Chen, Tao, Li, Ming, Liang, Jia, Chen, Kunying, Zhang, Jialing, Chen, Xu, Chen, Qi, Li, Guoming
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Sprache:eng
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Zusammenfassung:Insulin resistance (IR) is associated with a variety of cardiovascular diseases, but there are few studies on the correlation between IR and calcified aortic stenosis (CAS). In this study, the triglyceride-glucose (TyG) index, which reflects IR, was used to investigate the correlation between IR and CAS. The study included 183 elderly patients who were diagnosed with CAS by transthoracic echocardiography. The patients were matched 1:1 according to age and sex, and elderly patients who were hospitalized during the same period and underwent transthoracic echocardiography without aortic stenosis were included as the control group. The relationship between the TyG index and CAS was analyzed by a multivariable logistic regression model, curve fitting and trend test. Multivariate logistic regression analysis showed that the TyG index as a continuous variable was negatively associated with CAS (P 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-023-42206-x