A Comparison of Betadine, Sterillium and Silver Nanocolloid Immediate Effect on Surgical Hand Antiseptic

Background and Aim: To reduce surgical site infections and its complications, hand antiseptic is performed on the basis of product type either by rubbing or washing method. Silver Nanocolloid is a wide range disinfectant entered in world and also Iran markets as a surgical hand antiseptic, but any study about this subject hasn’t yet conducted. The aim of this study is comparing of Betadine, Sterillium and Silver Nanocolloid immediate effect on surgical hand antiseptic. Materials and Methods: This study design was randomized cross-over trial. Betadine, Sterillium, and Silver Nanocolloid with specific volume, duration (according to manufacturers’ instructions), and intervals (at least 24 hours) is conducted on 30 volunteer's hands. They occupy in operating room of hospital. Immediately after hands antisepsis, the samples were taken from the subject’s hands, transported to the blood agar plate, and plates were taken to the laboratory. In laboratory was incubated in 36 ± 1 degrees centigrade for 24 hours. For any growth medium, positive or negative of colony forming is surveyed and statistical analyses were conducted by SPSS software. Results: There’s not a statistically significant difference between negative cultures of Betadine and Sterillium, but negative culture of Betadine 20 (66.7%) and Sterillium 18 (60%), each of them separately, is significantly greater than Silver Nanocolloid 30 (10%) (P < 0.0001). 1 and 4 subjects experience much allergic reaction on their hands, respectively by using Sterillium and Silver Nanocolloid.Conclusions: The immediate antiseptic effects of Betadine and Sterillium are the same that conform to other studies and more than Silver Nanocolloid.