Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity

The titanium implant was treated with plasma electrolytic oxidation and subsequent ionic exchange and thermal treatment in order to obtain bioactive layer consisting of titanium oxide, calcium and sodium titanates and hydroxyapatite, as confirmed by X-ray diffraction (XRD). Scanning electron microsc...

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Veröffentlicht in:	Journal of applied biomaterials & functional materials 2021, Vol.19, p.2280800018822252-2280800018822252
Hauptverfasser:	Magić, Marko, Čolović, Božana, Vasilijić, Saša, Tadić, Nenad, Stojadinović, Stevan, Jokanović, Vukoman
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatibility Calcium oxide Cell adhesion Coatings Cytotoxicity Electrolytic cells Heat treatment Hydroxyapatite Iodides Light microscopy Lime Microscopy Optical microscopy Oxidation Phase composition Propidium iodide Scanning electron microscopy Sodium titanate Titanates Titanium Titanium oxide Titanium oxides Toxicity X-ray diffraction
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Beschreibung
Zusammenfassung:	The titanium implant was treated with plasma electrolytic oxidation and subsequent ionic exchange and thermal treatment in order to obtain bioactive layer consisting of titanium oxide, calcium and sodium titanates and hydroxyapatite, as confirmed by X-ray diffraction (XRD). Scanning electron microscopy (SEM) revealed that the given method, besides corresponding phase composition, enables suitable nanotopology for cell attachment and proliferation. Cytotoxicity investigations by MTT, LDH and propidium iodide assays and light microscopy showed that these coatings were not toxic to L929 cells.
ISSN:	2280-8000 2280-8000
DOI:	10.1177/2280800018822252