Evaluation of Serum TSH and Free T4 Levels in Migraine Patients

Aim: Migraine is a common neurovascular inflammatory disease that causes disability and is characterized by recurrent headache attacks. The role of thyroid regulation in migraine is poorly understood, and data are conflicting. The aim of this study is to evaluate the association of thyroid hormone levels and migraine types and headache severity. Materials and Methods: One hundred-fifty migraine patients enrolled in this retrospective study. Demographic and clinical characteristics of the patients, migraine subtypes, frequency and severity, serum thyrothytropine (TSH), and free thyroxin levels were evaluated from records. The Migraine Disability Assessment Questionnaire (MIDAS) and Visual Analog Scale (VAS) were used to assess the severity of migraine. Data analysis was performed. Results: The mean age was 40.40[+ or -]10.84 years, and the female to male ratio was 5.1: 1. No significant relationship was found between thyroid hormone levels and headache characteristics of migraine patients and migraine severity (p>0.05). There was no significant relationship between VAS and MIDAS values and TSH levels (p=0.973). Conclusion: Migraine and thyroid diseases are common diseases in the society. Thyroid diseases and thyroid function tests should be evaluated together when determining the characteristics of migraine and the headache severity. Our data suggest that there is no relationship between thyroid hormone levels and migraine subtypes and severity. Further studies are needed in order to confirm this association. Keywords: Migraine, serum TSH, serum free T4 Amac: Migren, tekrarlayan bas agrisiataklari ile karakterize, dizabilitiye neden olan ve sik gorulen norovaskuler enflamatuvar bir hastaliktir. Tiroid regulasyonunun migrendeki rolu tam olarak anlasilamamistir ve veriler celiskilidir. Bu calismanin amacitiroid hormon duzeyleri ile migren tipleri ve bas agrisisiddeti arasindaki iliskiyi degerlendirmektir. Gerec ve Yontem: Calismaya 150 migren hastasidahil edildi. Hastalarin demografik ve klinik ozellikleri, migren alt tipleri, sikligive siddeti, serum tirotropin (TSH), serbest tiroksin duzeyleri kayit edildi. Migrenin siddetini degerlendirmek icin Migren Dizabilite Degerlendirme Anketi (MIDAS) ve Gorsel Analog Skala (VAS) kullanildi. Verilerin analizi yapildi. Bulgular: Hastalarin yas ortalamasi40,40[+ or -]10,84 yil, kadin erkek orani5.1: 1 idi. Migren hastalarinin tiroid hormon duzeyleri ile bas agrisiozellikleri ile migren siddeti arasinda anlamlibir ilisk