Diversity of Francisella tularensis subsp. holarctica lineages, China

We analyzed 10 isolates of Francisella tularensis subspecies holarctica from China and assigned them to known clades by using canonical single-nucleotide polymorphisms. We found 4 diverse subtypes, including 3 from the most basal lineage, biovar japonica. This result indicates unprecedented levels o...

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Veröffentlicht in:	Emerging infectious diseases 2014-07, Vol.20 (7), p.1191-1194
Hauptverfasser:	Wang, Yanhua, Peng, Yao, Hai, Rong, Xia, Lianxu, Li, Hang, Zhang, Zhikai, Cai, Hong, Liang, Ying, Shen, Xiaona, Yu, Dongzheng, Birdsell, Dawn, Wagner, David M, Keim, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis bacteria canSNP China Cladistic analysis Dispatch Francisella tularensis - genetics Francisella tularensis subsp. holarctica Genetic polymorphisms Humans Phylogeny phylogeography Phylogeography - methods Polymorphism, Single Nucleotide - genetics SNP Tularemia - microbiology
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Beschreibung
Zusammenfassung:	We analyzed 10 isolates of Francisella tularensis subspecies holarctica from China and assigned them to known clades by using canonical single-nucleotide polymorphisms. We found 4 diverse subtypes, including 3 from the most basal lineage, biovar japonica. This result indicates unprecedented levels of diversity from a single region and suggests new models for emergence.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2007.130931