Familial hyperlipidemia: Resolving a case using evidence-based medicine

Background: familial hypercholesterolemia (FH) and familial hyperlipidemia combined (HFC) are metabolic disorders of lipids associated with increase of the risk for cerebrovascular disease. Clinical case: 8-years-old Indigenous child with HFC presented right hemiparesis, motor aphasia and right cent...

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Veröffentlicht in:	Revista de la Facultad Ciencias de la Salud, Universidad del Cauca Universidad del Cauca, 2011-03, Vol.13 (1), p.20-26
Hauptverfasser:	Edison Benavides-Hernández, Alexander Burbano-Imbachí, Hernando Almonacid-Córdoba, Cristina Collazos-Cerón, Victor Castro-Cruz, Álvaro Bastidas-Velasco, Andrea salas-Mesías, Jaime Bonilla-Medina, Álvaro Narváez-Gómez, Mario Delgado-Noguera
Format:	Artikel
Sprache:	spa
Schlagworte:	Niño, Hiperlipidemia Familiar Combinada, Estatinas, Accidente Cerebrovascular, Hipercolesterolemia, Medicina Basada en Evidencia, Child
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Zusammenfassung:	Background: familial hypercholesterolemia (FH) and familial hyperlipidemia combined (HFC) are metabolic disorders of lipids associated with increase of the risk for cerebrovascular disease. Clinical case: 8-years-old Indigenous child with HFC presented right hemiparesis, motor aphasia and right central facial paralysis for a cerebral ischemic accident; in addition, he had altered lipid profile and family history of hypercholesterolemia. Methodology: this article used patient`s therapeutic approach using evidence-based medicine (EBM), started from a structured clinical question and PubMED search. Four systematic reviews were included. Discussion: statins are safe in children with HF and HFC are effective in improving lipid profile. EBM methodology could help to solve similar therapeutic problems.
ISSN:	0124-308X 2538-9971