Long-term sequelae are highly prevalent one year after hospitalization for severe COVID-19

Many coronavirus disease 2019 (Covid-19) survivors show symptoms months after acute illness. The aim of this work is to describe the clinical evolution of Covid-19, one year after discharge. We performed a prospective cohort study on 238 patients previously hospitalized for Covid-19 pneumonia in 202...

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Veröffentlicht in:	Scientific reports 2021-11, Vol.11 (1), p.22666-22666, Article 22666
Hauptverfasser:	Bellan, Mattia, Baricich, Alessio, Patrucco, Filippo, Zeppegno, Patrizia, Gramaglia, Carla, Balbo, Piero Emilio, Carriero, Alessandro, Amico, Chiara Santa, Avanzi, Gian Carlo, Barini, Michela, Battaglia, Marco, Bor, Simone, Cantaluppi, Vincenzo, Cappellano, Giuseppe, Ceruti, Federico, Chiocchetti, Annalisa, Clivati, Elisa, Giordano, Mara, Cuneo, Daria, Gambaro, Eleonora, Gattoni, Eleonora, Loro, Alberto, Manfredi, Marcello, Morosini, Umberto, Murano, Francesco, Paracchini, Elena, Patti, Giuseppe, Pinato, David James, Raineri, Davide, Rolla, Roberta, Sainaghi, Pier Paolo, Tricca, Stefano, Pirisi, Mario
Format:	Artikel
Sprache:	eng
Schlagworte:	631/326 631/326/596 Aged Carbon monoxide Carbon Monoxide - metabolism Complications Computed tomography Coronaviruses COVID-19 COVID-19 - complications COVID-19 - diagnosis COVID-19 - diagnostic imaging COVID-19 - epidemiology Female Hospitalization Humanities and Social Sciences Humans Italy - epidemiology Logistic Models Male Mental Health Middle Aged Motor Activity multidisciplinary Patient Acuity Patient Discharge Patients Post traumatic stress disorder Prevalence Prospective Studies Pulmonary Diffusing Capacity Respiratory function Respiratory Function Tests Science Science (multidisciplinary) Stress Disorders, Post-Traumatic - epidemiology Stress Disorders, Post-Traumatic - etiology Survivors Tomography, X-Ray Computed Walk Test
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Zusammenfassung:	Many coronavirus disease 2019 (Covid-19) survivors show symptoms months after acute illness. The aim of this work is to describe the clinical evolution of Covid-19, one year after discharge. We performed a prospective cohort study on 238 patients previously hospitalized for Covid-19 pneumonia in 2020 who already underwent clinical follow-up 4 months post-Covid-19. 200 consented to participate to a 12-months clinical assessment, including: pulmonary function tests with diffusing lung capacity for carbon monoxide (DLCO); post-traumatic stress (PTS) symptoms evaluation by the Impact of Event Scale (IES); motor function evaluation (by Short Physical Performance Battery and 2 min walking test); chest Computed Tomography (CT). After 366 [363–369] days, 79 patients (39.5%) reported at least one symptom. A DLCO
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-021-01215-4