Mutation detection and inhibitor risk in Iranian patients with Hemophilia A: Six novel mutations

Mutation detection and inhibitor risk in Iranian patients with Hemophilia A: Six novel mutations

This investigation facilitates a better understanding of inhibitor development, the critical treatment morbidity in HA patients. Furthermore, six novel mutations are reported, which would expand the mutation spectrum of the F8 gene. This investigation facilitates a better understanding of inhibitor...

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Veröffentlicht in:Clinical case reports 2020-12, Vol.8 (12), p.2976-2985
Hauptverfasser: Nasirnejad Sola, Farzaneh, Morovvati, Saeid, Sabetghadam Moghadam, Mitra, Entezari, Malihe
Format: Artikel
Sprache:eng
Schlagworte:
Case Report
Case Reports
Circumcision
factor VIII gene
Family medical history
Genetic counseling
Hemophilia
hemophilia A
inhibitor risk
Mutation
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Zusammenfassung:This investigation facilitates a better understanding of inhibitor development, the critical treatment morbidity in HA patients. Furthermore, six novel mutations are reported, which would expand the mutation spectrum of the F8 gene. This investigation facilitates a better understanding of inhibitor development, the critical treatment morbidity in HA patients. Furthermore, six novel mutations are reported, which would expand the mutation spectrum of the F8 gene.
ISSN:2050-0904
2050-0904
DOI:10.1002/ccr3.3294