Predictors of subclinical atherosclerosis in HIV

Cardiovascular disease is a major cause of morbidity and mortality in people with HIV. The detection of subclinical atherosclerosis through vascular ultrasound allows us to identify patients at an increased risk of cardiovascular disease as a primary prevention strategy; this test is not routine. Ou...

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Veröffentlicht in:BMC infectious diseases 2023-01, Vol.23 (1), p.17-17, Article 17
Hauptverfasser: Fernández Soto, Julia, Romero-Jiménez, Manuel J, Alarcón García, José Carlos, Bonet Estruch, Elena, Sánchez Ramos, José Luís, Castaño López, Miguel Ángel
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Sprache:eng
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Zusammenfassung:Cardiovascular disease is a major cause of morbidity and mortality in people with HIV. The detection of subclinical atherosclerosis through vascular ultrasound allows us to identify patients at an increased risk of cardiovascular disease as a primary prevention strategy; this test is not routine. Our objective is to identify predictors of subclinical atherosclerosis in a population with HIV. People with HIV infection were selected for primary prevention and underwent carotid and femoral ultrasound to detect atheromatous plaques. Logistic regression analysis including vascular risk factors was performed to predict the presence of atherosclerosis. One hundred eighty-three patients were included, 54% of whom were smokers; the mean duration of HIV infection was 9.52 years, and all patients were undergoing antiretroviral treatment. Subclinical atherosclerosis was present in 62.29% of the patients; 83.32% had plaque in the carotid territory, 57.93% in the femoral territory and 25.6% in both vascular territories. Compared to those without atherosclerosis, patients with atherosclerosis were on average 5.35 years older (53.86 vs. 48.51, p 
ISSN:1471-2334
1471-2334
DOI:10.1186/s12879-022-07976-1