Sexually dimorphic neuronal responses to social isolation

Many species use social networks to buffer the effects of stress. The mere absence of a social network, however, may also be stressful. We examined neuroendocrine, PVN CRH neurons and report that social isolation alters the intrinsic properties of these cells in sexually dimorphic fashion. Specifica...

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Veröffentlicht in:eLife 2016-10, Vol.5
Hauptverfasser: Senst, Laura, Baimoukhametova, Dinara, Sterley, Toni-Lee, Bains, Jaideep Singh
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Sprache:eng
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Zusammenfassung:Many species use social networks to buffer the effects of stress. The mere absence of a social network, however, may also be stressful. We examined neuroendocrine, PVN CRH neurons and report that social isolation alters the intrinsic properties of these cells in sexually dimorphic fashion. Specifically, isolating preadolescent female mice from littermates for
ISSN:2050-084X
2050-084X
DOI:10.7554/elife.18726