Antibacterial Activity of Biosurfactant extracted from Streptococcus thermophilus and Its effect on some Biochemical Parameters in Male Rats

Streptococcus Thermophilus belongs to the group of lactic acid bacteria. The current study aims to identify the role of the biosurfactant produced by S. thermophilus bacteria, showing its importance in limiting the growth of pathogens and its effect on the biochemical parameters of male rats. S. thermophilus bacteria were isolated from local cheese, 120 different samples were collected from the human body (urine, sputum, wounds), and the biosurfactant was extracted from the bacteria. the active groups of biosurfactant components were detected and the antibacterial activity was tested on some biochemical parameters in male rats. 42 infected samples were distributed between 16 for urine, 11 for sputum and 15 for wound samples. The results showed that the highest percentage of infection with Staphylococcus aureus was 12 (28.57%), while the lowest Staphylococcus epidermidis was 3 (7.14%). The qualitative tests showed that the biosurfactant contains many active components such as tannins, carbohydrates, phenols, flavonoids, and sapindales, while does not contain triterpenoids. The results of the statistical analyses to anti-bacterial activity showed a significant increase (p