2-methoxyethanol as an alternative reaction solvent for the synthesis of 1,5-benzodiazepines under microwave irradiation

2-methoxyethanol as an alternative reaction solvent for the synthesis of 1,5-benzodiazepines under microwave irradiation

An improved condensation reaction between substituted 2'hydroxychalcones and o-phenylenediamine using piperidine in 2-methoxyetahnol as an efficient and alternative reaction medium. The clean reaction conditions, easy work up, time saving and higher yields are notable advantages of present meth...

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Veröffentlicht in:Orbital : The Electronic Journal of Chemistry 2011-07, Vol.3 (3), p.144-149
Hauptverfasser: Zangade, Sainath, Mokle, Shyam, Chavan, Shivaji, Vibhute, Yeshwant
Format: Artikel
Sprache:eng
Schlagworte:
2-methoxyethanol
2’-hydroxychalcones
Antianxiety agents
Benzodiazepines
green chemistry
microwave irradiation
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Zusammenfassung:An improved condensation reaction between substituted 2'hydroxychalcones and o-phenylenediamine using piperidine in 2-methoxyetahnol as an efficient and alternative reaction medium. The clean reaction conditions, easy work up, time saving and higher yields are notable advantages of present method. Keywords: 2'-hydroxychalcones; 2-methoxyethanol; green chemistry; microwave irradiation
ISSN:1984-6428
1984-6428
DOI:10.17807/orbital.v3i3.240