Predictive value of heart rate in patients with acute type A aortic dissection: a retrospective cohort study

ObjectiveHeart rate (HR) is a risk factor of mortality in many cardiovascular diseases but no clinical studies have focused on the association between HR and prognosis in patients with acute type A aortic dissection (ATAAD). This study aimed to evaluate the association between HR and long-term mortality and establish the criteria of HR in patients with ATAAD who underwent total aortic arch replacement combined with the frozen elephant trunk (TAR+FET).Design, setting and participantsRetrospective cohort study that studied all consecutive patients with ATAAD who underwent TAR+FET in the Fuwai Hospital between 2009 and 2015.Main outcomes and measures30-day postoperative, and estimated long-term mortality.ResultsOverall, 707 patients with ATAAD who underwent TAR+FET were followed up for a median duration of 29 months (range, 5–77 months). In multivariate logistic analysis, HR (p80 bpm is independently associated with elevated long-term mortality for patients with ATAAD.