Changes in somatic disease incidents during opioid maintenance treatment: results from a Norwegian cohort study

ObjectivesTo examine the effect of opioid maintenance treatment (OMT) on somatic morbidity in a cohort of OMT patients.DesignRetrospective cohort study.SettingOMT programme in two Norwegian counties.Participants200 OMT patients, participation rate 71.2%.Main outcome measuresIncidence rates (IR) befo...

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Veröffentlicht in:BMJ open 2011-01, Vol.1 (1), p.e000130-e000130
Hauptverfasser: Skeie, Ivar, Brekke, Mette, Gossop, Michael, Lindbaek, Morten, Reinertsen, Even, Thoresen, Magne, Waal, Helge
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Sprache:eng
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Zusammenfassung:ObjectivesTo examine the effect of opioid maintenance treatment (OMT) on somatic morbidity in a cohort of OMT patients.DesignRetrospective cohort study.SettingOMT programme in two Norwegian counties.Participants200 OMT patients, participation rate 71.2%.Main outcome measuresIncidence rates (IR) before, during and after OMT for acute/subacute hospital-treated somatic disease incidents (drug-related, non-drug-related, injuries) and rates for inpatient days and outpatient treatment contacts.ResultsIR for drug-related hospital treatment episodes were 76% lower during compared to before OMT (before versus during incidence rate ratio (IRR) 4.2 (95% CI 2.9 to 6.2), p
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2011-000130