Zika Virus Persistence and Higher Viral Loads in Cutaneous Capillaries Than in Venous Blood

We collected venous and capillary serum samples from 21 Zika virus‒infected patients on multiple days after symptom onset and found RNA load was higher and median duration of virus detection significantly longer in capillary than in venous blood. These findings raise questions about the role of the...

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Veröffentlicht in:	Emerging infectious diseases 2017-11, Vol.23 (11), p.1910-1911
Hauptverfasser:	Matheus, Séverine, de Laval, Franck, Moua, David, N'Guyen, Christophe, Martinez, Enguerrane, Rousset, Dominique, Briolant, Sébastien
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis Capillaries - virology capillary blood samples Chikungunya virus Disease transmission Female Genetic vectors Human health and pathology Humans Life Sciences Male Middle Aged persistence Research Letter RNA, Viral - blood vector-borne infections Veins - virology venous samples Viral Load Zika Zika Virus Zika Virus Infection - blood Zika Virus Infection - virology Zika Virus Persistence and Higher Viral Loads in Cutaneous Capillaries Than in Venous Blood
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Zusammenfassung:	We collected venous and capillary serum samples from 21 Zika virus‒infected patients on multiple days after symptom onset and found RNA load was higher and median duration of virus detection significantly longer in capillary than in venous blood. These findings raise questions about the role of the capillary compartment in virus transmission dynamics.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2311.170337